Canadian
health authorities have agreed to allow doctors to prescribe the COX-2 inhibitor
Vioxx (rofecoxib) for the relief of rheumatoid arthritis in adults. "Rheumatoid
arthritis is one of the most painful and debilitating forms of arthritis,"
said Dr. Alfred Cividino, rheumatologist and associate clinical professor at McMaster
University in Canada.
Cividino said
Vioxx offers physicians and their patients a better tolerated
alternative to traditional non-steroidal anti-inflammatory drugs
(NSAIDs) in managing the pain caused by rheumatoid arthritis.
Citing
the Vigor study that involved over 8,000 patients with rheumatoid arthritis in
22 countries, Merck Frosst, the Canadian subsidiary of Merck, said Vioxx significantly
reduced the risk of serious gastrointestinal events by 54 percent compared to
naproxen.
Naproxen is
one of the NSAIDs most commonly used to treat pain associated
with rheumatoid arthritis.
Other
sources: Merck Frosst |