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A phase I
safety trial of MX-1094, a nonsteroidal antiinflammatory drug,
for the treatment of arthritis has begun in the Netherlands, according
to Medinox, the drug's manufacturer.
"We are
excited about moving forward into clinical development with this
promising new compound," said Monte Lai, Medinox's President
and CEO. "We believe that MX-1094 will meet the need for
safer NSAIDs and has the potential to be a leading clinical therapy."
The randomized,
double-blind, placebo-controlled, escalating single- and multiple-dose
study also will evaluate the tolerability and pharmacokinetics
of the drug in healthy volunteers.
The trial
should be completed by the end of 2002.
Other
sources: Medinox
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