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Corticosteroids,
such as prednisone, cortisone, solumedrol, and hydrocortisone,
are used in varying doses to decrease inflammation of the joints
caused by arthritis.
They can be
given by mouth, in creams applied to the skin, or by injection.
Corticosteroid
dosages vary widely. The specific dosage your doctor prescribes
will be based on your disease and the goals of treatment, and
low doses (10 mg of prednisone or less) may be sufficient for
the joint inflammation associated with rheumatoid arthritis.
While doses
are sometimes raised during times of severe flares, the goal is
to keep dosages low or to taper them as soon as possible.
Doctors often
seek to keep corticosteroid doses low by also prescribing disease-modifying
antirheumatic drugs (DMARDs) in conjunction
with them.
Short-term
side effects of corticosteroids include swelling, increased appetite,
weight gain, and emotional ups and downs. These side effects generally
stop when the drug is stopped.
It can be
dangerous to stop taking corticosteroids suddenly, so it is very
important that the doctor and patient work together when changing
the corticosteroid dose.
Side effects
that may occur after long-term use of corticosteroids include
stretch marks, excessive hair growth, osteoporosis, high blood
pressure, damage to the arteries, high blood sugar, infections,
and cataracts.
If you have
only a few affected joints, your doctor may be able to bypass
the side effects of regular corticosteroid use by injecting a
corticosteroid compound directly into them.
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